Known as ‘IHU’, the B.1.640.2 variant has been reported by researchers at institute IHU Mediterranee Infection in at least 12 cases, and has been linked to travel to African country Cameroon. Here’s all you need to know about this new strain:
1. Scientists in France have identified this new, much more mutated strain- named IHU B.1.640.2 variant. The B.1.640.2 has not been identified in other countries so far or labelled a variant under investigation by the World Health Organization (WHO).
2. It was discovered by the academics at the institute IHU Mediterranee Infection and researchers say that it contains 46 mutations, more than Omicron. With more mutations, the new variant becomes more resistant to vaccines and infectious.
3. At least 12 cases of the new variant have been reported near Marseilles, and has been linked to travel to the African country Cameroon.
4. According to the researchers, the index (first) case was an adult diagnosed positive by RTPCR performed in a laboratory on a nasopharyngeal sample collected in mid-November last year.
5. The researchers also said that it is too early to speculate on how this variant behaves as far as infection and protection from vaccines is concerned.
6. The yet-to-be peer-reviewed study, posted on the preprint repository MedRxiv on December 29, revealed that IHU has 46 mutations and 37 deletions resulting in 30 amino acid substitutions and 12 deletions. Amino acids are molecules that combine to form proteins, and both are the building blocks of life. Fourteen amino acid substitutions, including N501Y and E484K, and nine deletions are located in the spike protein.
7. Most currently used vaccines are targeted at the spike protein of SARS-CoV-2, which the virus uses to enter and infect the cells. N501Y and E484K mutations were earlier also found in Beta, Gamma, Theta and Omicron variants.
8. The researchers said that the “mutation set and phylogenetic position of the genomes obtained indicate based on our previous definition a new variant we named IHU.” The data is another example of the unpredictability of the emergence of SARS-CoV-2 variants, and of their introduction in a given geographical area from abroad, they said.
9. Eric Feigl-Ding, an epidemiologist, on Tuesday posted a long Twitter thread in which he said that new variants keep emerging but it does not necessarily mean they will be more dangerous. “What makes a variant more well-known and dangerous is its ability to multiply because of the number of mutations it has in relation to the original virus,” Feigl-Ding tweeted. “This is when it becomes a “variant of concern” – like Omicron, which is more contagious and more past immunity evasive. It remains to be seen in which category this new variant will fall,” he said.
10. Many countries are currently experiencing a spike in Covid-19 cases driven by the Omicron variant which was first identified in South Africa and Botswana in November last year. Since then, the variant of concern has spread to over 100 countries. In India, a total of 1,892 cases of Omicron variant have been detected across 23 states and Union Territories so far.
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